Various researchers have proposed different approaches for implementing GIS in developing countries. One of them is an integrative framework from which the GIS implementation is typically linked with the implementation of other policies or programs. There is little discussion on benefits and risks of this approach particularly in health. Therefore, this case study aims at exploring this approach, particularly challenges being associated with it because there are observations of such practices in Malawi. It has been observed that it is possible to link GIS implementation activities with those of other programs or projects. This link helps to share resources: e.g. human, tools and time but more attention should be on priorities of implementation activities and utilization of such resources. However, it is not all activities that can be linked due to some factors. Some decisions need to be made ensuring that the linking is possible.